The NRC warns against high intake of ascorbic acid stating the following. The data support the hypothesis that these behavioural effects in cats are due to drug action at both 5-HT and dopamine receptors and that the action of LSD at dopamine receptors is modulated by ascorbic acid. Ascorbic acid is manufactured by most animals except for some birds fish guinea pigs fruit bats and primates and humans.
Furthermore these pets do not need vitamin supplementation under normal circumstances. Holistic veterinarians usually prefer natural vitamin C supplementation when indicated although studies using the complementary therapy called. High intake of ascorbic acid may act as a prooxidant and induce lipid peroxidation.
For several decades now there has been information that ascorbic acid or vitamin C can help in treating. Simply supplementing ascorbic acid is not the same as supplying vitamin C. In dogs and cats ascorbic acid is manufactured in the liver and normally does not need to be supplemented.
Therapeutic Effects of Parenteral Vitamin C Ascorbic Acid on Struvite Crystalluria in Domestic Male Cats. Pretreatment with ascorbic acid 500 mg kg-1 ip antagonized the behavioural effects of lysergic acid diethylamide LSD and apomorphine but not 5-methoxy-NN-dimethyltryptamine in cats. Iranian Journal of Veterinary Medicine 133 233-242.
Cats are prone to various types of malignancy including Feline Leukemia Virus Squamous cell carcinoma fibrosarcoma lymphoma and mammary cancer. So why do some think it could be bad for cats. Vitamin C ascorbic acid The liver of cats has the key enzyme L-gulono-Y-lactone oxidase EC 11.